How do FLiRT subvariants KP.2, KP.3, and KP.1.1 differ from each other ?

 The FLiRT subvariants KP.2, KP.3, and KP.1.1 are new mutations within the SARS-CoV-2 lineage that exhibit slight differences due to specific spike protein mutations. These subvariants evolved from the JN.1 variant, inheriting similar characteristics but with unique adaptations that may affect immune evasion and transmission efficiency.

Each subvariant—KP.2, KP.3, and KP.1.1—contains specific mutations at positions like 456 and 346 on the spike protein, which help the virus evade antibody detection. While KP.2 and KP.3 are closely monitored for their transmissibility and immune evasion capacity, they do not show significant differences in the severity of symptoms compared to earlier variants like JN.1. The primary risk associated with these subvariants is their ability to evade immunity, leading to mild increases in COVID-19 cases in vulnerable populations, especially the elderly and immunocompromised​.

My Care Labs is prepared to address the evolving COVID-19 landscape by offering responsive testing and vaccination options. Through updated PCR and rapid antigen tests, My Care Labs can detect the latest variants, including those in the JN.1 family, ensuring reliable diagnosis for the FLiRT subvariants. In addition to testing, My Care Labs provides booster vaccinations tailored to the latest variant lineages, helping individuals strengthen their immunity and reduce severe illness risks. This comprehensive approach aligns with public health recommendations and provides accessible, timely support for communities at higher risk, such as the elderly and those with preexisting conditions.

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